1. George Broughton, I., Janis, J.E. and Attinger, C.E., 2006. Wound healing: an overview. Plastic and reconstructive surgery. 117(7S): 1e-S-32e-S. doi: 10.1097/01.prs.0000222562.60260.f9 [ DOI] 2. George Broughton, I., Janis, J.E. and Attinger, C.E., 2006. The basic science of wound healing. Plastic and reconstructive surgery. 117(7S): 12S-34S. doi: 10.1097/01.prs.0000225430.42531.c2 [ DOI] 3. Pourmahdi, O., Modshtagh, I., Moadi gardeshi, T. and Gholami-Ahangarn, M., 2023. Comparison of the effect of ointment containing Citrus aurantium extract with phenytoin ointment on wound healing. Journal of Animal Environment. 14(4): 101-108. doi: 10.22034/ AEJ.2022.317994.2699 (In Persian) [ DOI] 4. Tabib, M., 2011. Genetic diversity of Eretmochelys imbricata in Kish and Qeshm islands using D-loop sequencing of mitochondrial genome. Journal of Animal Environment. 3(1): 1-6. (In Persian) 5. Krizanova, O., Penesova, A., Sokol, J., Hokynkova, A., Samadian, A. and Babula, P., 2022. Signaling pathways in cutaneous wound healing. Front Physiology. 13: 1030851. doi: 10.3389/fphys.2022.1030851 [ DOI] 6. Yudi, D., Jinyuan, Ch., Jinyu, H., Xushan, Y., Xudong, Z., Sijie, Y. and Wenzhen, L., 2020. Preparation and characterization of cellulose/flaxseed gum composite hydrogel and its hemostatic and wound healing functions evaluation. Cellulose. 27: 3971-3988. 7. Sharifi, R., Rastegar, H., Kamalinejad, M., Dehpour, A.R., Tavangar, S.M., Paknejad, M., Mehrabani Natanzi, M., Ghannadian, N., Akbari, M. and Pasalar, P., 2012. Effect of topical application of silymarin (Silybum marianum) on excision wound healing in albino rats. Acta Medica Iranica. 50(9): 583-588. PMID: 23165806 8. Purohit, S.K, Solanki, R., Soni, S.K. and Mathur, V., 2012. Experimental evaluation of Aloe vera leaves pulp as topical medicament on wound healing. International Journal of Pharmacological Research. 2(3): 110-112. doi: 10.7439/ijpr.v2i3.702 [ DOI] 9. Asadpour, R., 2013. Protective effects of garlic aquous extract (Allium sativum), vitamin E, and N-acetylcysteine on reproductive quality of male rats exposed to lead. in Veterinary research forum: an international quarterly journal. Faculty of Veterinary Medicine, Urmia University, Urmia, Iran. (In Persian) 10. Tang, W. and Eisenbrand, G., 2013. Chinese drugs of plant origin: chemistry, pharmacology, and use in traditional and modern medicine. Springer Science & Business Media. 1056 p. 11. Khan, K.Y., Khan, M., Ahmad, M. and Hussain, I., 1930. Hypoglycemic potential of genus Ficus L.: A review of ten years of plant based medicine used to cure diabetes (2000-2010). Journal of Applied Pharmaceutical Science. 1(6): 223-227. 12. Farahpour, M. and Habibi, M., 2012. Evaluation of the wound healing activity of an ethanolic extract of Ceylon cinnamon in mice. Veterinární Medicína. 57(1): 53-57. doi: 10.17221/4972-VETMED [ DOI] 13. Nesbitt, P.D. and Thompson, L.U., 1997. Lignans in homemade and commercial products containing flaxseed. Nutrition and Cancer. 29(3): 222-227. doi: 10.1080/01635589709514628 [ DOI] 14. Otranto, M., Do Nascimento, A.P. and Monte Alto Costa, A., 2010. Effects of supplementation with different edible oils on cutaneous wound healing. Wound Repair and Regeneration. 18(6): 629-636. doi: 10.1111/j.1524-475X.2010.00617.x [ DOI] 15. Farahpour, M.R., Taghikhani, H. and Habibi, M., 2011. Wound healing activity of flaxseed Linum usitatissimum L. in rats. African Journal of Pharmacy and Pharmacology. 5(21): 2386-2389. doi: 10.5897/AJPP11.258 [ DOI] 16. Goyal, A., Sharma, V., Upadhyay, N., Gill, S. and Sihag, M., 2014. Flax and flaxseed oil: an ancient medicine & modern functional food. Journal of Food Science and Technology. 51(9): 1633-1653. doi: 10.1007/s13197-013-1247-9 [ DOI] 17. Cunnane, S.C., Ganguli, S., Menard, C., Liede, A.C., Hamadeh, M.J., Chen, Z.Y., Wolever, T.M. and Jenkins, D.J., 1993. High α-linolenic acid flaxseed (Linum usitatissimum): some nutritional properties in humans. British Journal of Nutrition. 69(2): 443-453. doi: 10.1079/bjn19930046 [ DOI] 18. Rodriguez-Leyva, D., Dupasquier, C.M.C., McCullough, R., Pierce, G.N., 2010. The cardiovascular effects of flaxseed and its omega-3 fatty acid, alpha-linolenic acid. Canadian Journal of Cardiology. 26(9): 489-496. doi: 10.1016/s0828-282x(10)70455-4 [ DOI] 19. Thompson, L.U., Rickard, S.E., Orcheson, L.J. and Seidl, M.M., 1996. Flaxseed and its lignan and oil components reduce mammary tumor growth at a late stage of carcinogenesis. Carcinogenesis. 17(6): 1373-1376. doi: 10.1093/carcin/17.6.1373 [ DOI] 20. Prasad, K., 2005. Hypocholesterolemic and antiathero sclerotic effect of flax lignan complex isolated from flaxseed. Atherosclerosis. 179(2): 269-275. doi: 10.1016/j.atherosclerosis.2004.11.012 [ DOI] 21. Bloedon, L.T. and Szapary, P.O., 2004. Flaxseed and cardiovascular risk. Nutrition reviews. 62(1): 18-27. doi: 10.1111/j.1753-4887.2004.tb00002.x [ DOI] 22. Reza, G. and Mohammad, A., 2014. Novel advancements in wound healing. Journals of Birjand University of Medical Sciences. 21(1): 1-19. (In Persian) 23. Doillon, C.J., Dunn, M.J., Bender, E. and Silver, F.H., 1985. Collagen fiber formation in repair tissue: development of strength and toughness. Collagen and related research. 5(6): 481-492. doi: 10.1016/s0174.173 x(85)80002-9 [ DOI] 24. Velnar, T., Bailey, T. and Smrkolj, V., 2009. The wound healing process: an overview of the cellular and molecular mechanisms. Journal of International Medical Research. 37(5): 1528-1542. doi: 10.1177/14732300090 3700531 [ DOI] 25. Kirsner, R.S. and Eaglstein, W.H., 1993. The wound healing process. Dermatologic clinics. 11(4): 629-640. 26. Demling, R.H., 2009. Nutrition, anabolism, and the wound healing process: an overview. Eplasty. 9. 27. Enoch, S. and Leaper, D.J., 2008. Basic science of wound healing. Surgery. 26(2): 31-37. 28. Koch, A.E., Polverini, P.J., Kunkel, S.L., Harlow, L.A., DiPietro, L.A., Elner, V.M., Elner, S.G. and Strieter, R.M., 1992. Interleukin-8 as a macrophage derived mediator of angiogenesis. Science. 258(5089): 1798-1801. doi: 10.1126/science.1281554 [ DOI] 29. Czemplik, M., Kulma, A., Bazela, K. and Szopa, J., 2012. The biomedical potential of genetically modified flax seeds overexpressing the glucosyltransferase gene. BMC complementary and alternative medicine. 12(1): 1-10. doi: 10.1186/1472-6882-12-251 [ DOI] 30. Krizanova, O., Penesova, A., Sokol, J., Hokynkova, A., Samadian, A. and Babula, P., 2022. Signaling pathways in cutaneous wound healing. Front Physiology. 13: 1030851. doi: 10.3389/fphys.2022.1030851 [ DOI] 31. Farahpour, M., 2011. Wound healing activity of flaxseed Linum usitatissimum L. in rats. African Journal of Pharmacy and Pharmacology. 5. 32. Beroual, K., Agabou, A., Abdeldjelil, M.Ch., Boutaghane, N., Haouam, S. and Hamdi-Pacha, Y., 2017. Evaluation of crude flaxseed (Linum usitatissimum l) oil in burn wound healing in new zealand rabbits. African journal of traditional, complementary, and alternative medicines. 14(3): 280-286. doi: 10.21010/ajtcam.v14i3.29 [ DOI] 33. de Souza Franco, E., 2012. Effect of a Semisolid Formulation of Linum usitatissimum L. (Linseed) Oil on the Repair of Skin Wounds. Evidence-based complementary and alternative medicine. 270752. doi: 10.1155/2012/270752 [ DOI] 34. Al-Ahmad, B.M., 2020. Histopathological changes of the flaxseed extract on skin wound healing in diabetic rabbits. Open Access Macedonian Journal of Medical Sciences. 8(A): 881-892. doi: 10.3889/oamjms.2020.5145 [ DOI] 35. Rafiee, Sh., Nekouyian, N., Hosseini, S., Sarabandi, F., Chavoshi-Nejad, M., Mohsenikia, M., Yadollah-Damavandi, S., Seifaee, A., Jangholi, E., Eghtedari, D., Najafi, H. and Ashkani-Esfahani, S., 2017. Effect of Topical Linum usitatissimum on Full Thickness Excisional Skin Wounds. Trauma Monthly. 22(6): e64930. doi: 10.5812/traumamon.39045 [ DOI] 36. Gębarowski, T., Wiatrak, B., Janeczek, M., Żuk, M., Pistor, P. and Gąsiorowski, K., 2020. Were our Ancestors Right in Using Flax Dressings? Research on the Properties of Flax Fibre and Its Usefulness in Wound Healing. Oxidative Medicine and Cellular Longevity. 1682317. doi: 10.1155/2020/1682317 [ DOI] 37. Draganescu, D., Ibanescu, C., Tamba, B.I., Andritoiu, C.V., Dodi, G. and Popa, M.I., 2015. Flaxseed lignan wound healing formulation: Characterization and in vivo therapeutic evaluation. International Journal of Biological Macromolecules. 72: 614-623. doi: 10.1016/j. ijbiomac.2014.09.012 [ DOI] 38. Farahpour, M.R. and Fathollahpour, S., 2015. Topical co-administration of flaxseed and pistachio ointment promoted wound healing; evidence for histopathological features. Comparative Clinical Pathology. 24(6): 1455-1461. doi: 10.1007/s00580-015-2097-9 [ DOI] 39. Farahpour, M., 2014. Evaluation of the combined effect of St John's wort hydroethanolic flower extract and flaxseed oil on skin wound healing -in rats. Veterinary Clinical Pathology. 81(29): 417-426. 40. Deng, Y., Chen, J., Huang, J. and Yang, X., 2020. Preparation and characterization of cellulose/flaxseed gum composite hydrogel and its hemostatic and wound healing functions evaluation. Cellulose. 27(7): 3971-3988. doi: 10.1007/s10570-020-03055-3 [ DOI] 41. Styrczewska, M., Kostyn, A., Kulma, A., Majkowska Skrobek, G., Augustyniak, D., Prescha, A., Czuj, T. and Szopa, J., 2015. Flax fiber hydrophobic extract inhibits human skin cells inflammation and causes remodeling of extracellular matrix and wound closure activation. BioMed research international. 862391. doi: 10.1155/2015/862391 [ DOI] 42. Dogoury, H.G., Farahpour, M.R. and Amniattalab, A., 2014. Comparision effect of chamomile (Chamomilla recutita) hydroethanolic extract and flaxseed oil (Linum ustatissum) alone and simultaneous administration with nitrofurazone in wound healing process. Indian Journal of Fundamental and Applied Life Sciences. 5(1): 216-223. 43. Datta, H.S., Mitra, S.K. and Patwardhan, B., 2011. Wound healing activity of topical application forms based on ayurveda. Evidence-Based Complementary and Alternative Medicine. 134378. doi: 10.1093/ecam/nep015 [ DOI] 44. Bardaa, S., Chabchoub, N., Jridi, M., Moalla, D., Mseddi, M., Rebai, T. and Sahnoun, Z., 2016. The effect of natural extracts on laser burn wound healing. Journal of Surgical Research. 201(2): 464-472. doi: 10.1016/j.jss.2015.11.052 [ DOI] 45. Trabelsi, I., Ben Slima, S., Ktari, N., Bardaa, S., Elkaroui, K., Abdeslam, A. and Ben Salah, R., 2020. Purification, composition and biological activities of a novel heteropolysaccharide extracted from Linum usitatissimum L. seeds on laser burn wound. International Journal of Biological Macromolecules. 144: 781-790. doi: 10.1016/j.ijbiomac.2019.10.077 [ DOI] 46. Synytsya, A., Poučková, P., Zadinová, M., Troshchynska, Y., Štětina, J., Synytsya, A., Saloň, I. and Král, V., 2020. Hydrogels based on low-methoxyl amidated citrus pectin and flaxseed gum formulated with tripeptide glycyl-l-histidyl-l-lysine improve the healing of experimental cutting wounds in rats. International Journal of Biological Macromolecules. 165: 3156-3168. https://doi.org/10.1016/j.ijbiomac.2020.09.251 [ DOI] 47. Beroual, K., Agabou, A., Abdeldjelil, M.Ch., Boutaghane, N., Haouam, S. and Hamdi-Pacha, Y., 2017. Evaluation of crude flaxseed (Linum usitatissimum L.) oil in burn wound healing in New Zealand rabbits. African Journal of Traditional, Complementary and Alternative Medicines. 14(3): 280-286. doi: 10.21010/ajtcam.v14i3.29 [ DOI] 48. Abdul Jabbar, O., Kashmoola, M.A., Mustafa Al-Ahmad, B.E., Mokhtar, K.I., Muhammad, N., Abdul Rahim, R. and Qouta, L.A., 2019. The Effect of Flaxseed Extract on Skin Elasticity of The Healing Wound In Rabbits. IIUM Medical Journal Malaysia. 18(1): 5-12. https://doi.org/10.31436/imjm.v18i1.230 [ DOI] 49. Soleimani, M., Yousefzadeh, S., Salari, R., Mousavi Vahed, S.H. and Mazloum, S.R., 2019. The effects of flaxseed ointment on cesarean wound healing: randomized clinical trial. Iranian Journal of Obstetrics, Gynecology and Infertility. 22(9): 64-71. doi: 10.22038/ ijogi.2019.14003 (In Persian) [ DOI] 50. Masoumi, S., Ghanbari, A., Paryad, E., Kazemnezhad Leyli, E., Mahdavi-Roshan, M. and Mobayen, M., 2019. Effects of flaxseed oil and olive oil on markers of inflammation and wound healing in burn patients: a randomized clinical trial,9th national burn congress, Tehran,https://civilica.com/doc/1001863 (In Persian) 51. Babajafari, S., Akhlaghi, M., Mazloomi, S.M., Ayaz, M., Noorafshan, A., Jafari, P. and Hojhabrimanesh, A., 2018. The effect of isolated soy protein adjunctive with flaxseed oil on markers of inflammation, oxidative stress, acute phase proteins, and wound healing of burn patients; a randomized clinical trial. Burns. 44(1): 140-149. doi: 10.1016/j.burns.2017.05.014 [ DOI] 52. Soleimani, Z., Hashemdokht, F., Bahmani, F., Taghizadeh, M., Memarzadeh, M.R. and Asemi, Z., 2017. Clinical and metabolic response to flaxseed oil omega-3 fatty acids supplementation in patients with diabetic foot ulcer: A randomized, double blind, placebo controlled trial. Journal of Diabetes and its Complications. 31(9): 1394-1400. doi: 10.1016/j.jdiacomp.2017.06.010 [ DOI] 53. De Spirt, S., Stahl, W., Tronnier, H., Sies, H., Bejot, M., Maurette, J.M. and Heinrich, U., 2008. Intervention with flaxseed and borage oil supplements modulates skin condition in women. British Journal of Nutrition. 101(3): 440-445. doi: 10.1017/S0007114508020321 [ DOI] 54. Al-Mathkhury, H.J.F., Al-Dhamin, A.S. and Al-Taie, K.L., 2016. Antibacterial and antibiofilm activity of flaxseed oil. Antibact. Antibiofilm Act. Flaxseed Oil. 57(2B): 1086-1095. 55. Pagano, C., Baiocchi, C., Beccari, T., Blasi, F., Cossignani, L., Ceccarini, M.R., Orabona, C., Orecchini, E., Raimo, E.D., Primavilla, S., Salvini, L., Michele, A.D., Perioli, L. and Ricci, M., 2021. Emulgel Loaded with Flaxseed Extracts as New Therapeutic Approach in Wound Treatment. Pharmaceutics. 13(8): 1107. doi: 10.3390/pharmaceutics13081107 [ DOI] 56. Lovett, R., 1895. The Flaxseed-Meal Poultice as a Sterile Dressing. The Boston Medical and Surgical Journal. 132(14): 329-330. doi: 10.1056/NEJM189504041321404 [ DOI] 57. Gorshkova, T.A., Wyatt, S.E., Salnikov, V.V., Gibeaut, D.M., Ibragimov, M.R., Lozovaya, V.V. and Carpita, N.C., 1996. Cell-wall polysaccharides of developing flax plants. Plant Physiology. 110(3): 721-729 doi: 10.1104/pp.110.3.721. [ DOI] 58. Styrczewska, M., Kostyn, A., Kulma, A., Majkowska-Skrobek, G., Augustyniak, D., Prescha, A., Czuj, T. and Szopa, J., 2015. Flax Fiber Hydrophobic Extract Inhibits Human Skin Cells Inflammation and Causes Remodeling of Extracellular Matrix and Wound Closure Activation. BioMed Research International. 862391. doi: 10.1155/2015/862391 [ DOI] 59. Ferreira, M.C., Tuma Jr, P., Carvalho, V.F. and Kamamoto, F., 2006. Complex wounds. Clinics. 61(6): 571-578. doi: 10.1590/s1807-59322006000600014 [ DOI] 60. Percival, N.J., 2002. Classification of wounds and their management. Surgery (Oxford). 20(5): 114-117. doi: 10.1383/surg.20.5.114.14626 [ DOI] 61. Wild, T., Rahbarnia, A., Kellner, M., Sobotka, L. and Eberlein, T., 2010. Basics in nutrition and wound healing. Nutrition. 26(9): 862-866. doi: 10.1016/j.nut. 2010.05.008 [ DOI] 62. Beroual, K., Agabou, A., Abdeldjelil, M.Ch., Boutaghane, N., Haouam, S. and Hamdi-Pacha, Y., 2017. Evaluation of crude flaxseed (Linum usitatissimum L.) oil in burn wound healing in New Zealand rabbits. African Journal of Traditional, Complementary and Alternative Medicines. 14(3): 280-286. doi: 10.21010/ajtcam.v14i3.29 [ DOI] 63. Long, J.J., Fu, Y., Zu, Y., Li, J., Wang, W., Gu, Ch. And Luo, M., 2011. Ultrasound-assisted extraction of flaxseed oil using immobilized enzymes. Bioresource technology. 102(21): 9991-9996. doi: 10.1016/j.biortech.2011.07.104 [ DOI] 64. Tumen, I., Süntar, I., Keleş, H. and Küpeli Akkol, E., 2012. A therapeutic approach for wound healing by using essential oils of Cupressus and Juniperus species growing in Turkey. Evidence-based complementary and alternative medicine. 728281 doi: 10.1155/2012/728281 [ DOI] 65. Boelsma, E., Hendriks, H.F. and Roza, L., 2001. Nutritional skin care: health effects of micronutrients and fatty acids. The American journal of clinical nutrition. 73(5): 853-864. doi: 10.1093/ajcn/73.5.853 [ DOI] 66. Estevão, L.R.M., 2013. Effects of aroeira (Schinus terebinthifoliu Raddi) oil on cutaneous wound healing in rats. Acta Cirurgica Brasileira. 28(3): 202-209. doi: 10.1590/s0102-86502013000300008 [ DOI] 67. Rafiee, S., Nekouyian, N., Hosseini, S. and Sarabandi, F., 2017. Effect of topical linum usitatissimum on full thickness excisional skin wounds. Trauma Monthly. 22(6): e64930. doi: 10.5812/traumamon.39045 [ DOI] 68. Zimmerman, D. and Feng, P., 1978. Characterization of a prostaglandin‐like metabolite of linolenic acid produced by a flaxseed extract. Lipids. 13(5): 313-316. 69. Yadav, R.K., Singh, M., Roy, S., Ansari, M.N., Saeedan, A.S. and Kaithwas, G., 2018. Modulation of oxidative stress response by flaxseed oil: Role of lipid peroxidation and underlying mechanisms. Prostaglandins & other lipid mediators. 135: 21-26. doi: 10.1016/j.prostaglandins.2018.02.003 [ DOI] 70. Joshi, A., Hegde, M. and Zanwar, A., 2022. Flaxseed oil and palm olein blend to improve omega-6: Omega-3 ratio. Journal of Food Science and Technology. 59(2): 498-509. doi: 10.1007/s13197-021-05033-4 [ DOI]
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