|
Investigating the effects of conjugated linoleic acid and vitamin E emulsified on growth performance, blood parameters and immune system of Holstein calves
|
Behrooz Khalili   , Hossein Abdi Benemar * , Jamal Seifdavati , Mohammad Reza Zamanloo , Sayyad Seifzadeh , Afsaneh Talebniya |
|
|
|
Abstract: (781 Views) |
Introduction: A better understanding of the immune system of calves will lead to less use of antibiotics and the production of high-quality replacement heifers for dairy herds. The study aim was to investigate the effects of conjugated linoleic acid and vitamin E emulsion on growth performance, blood parameters and immune system of Holstein calves.
Materials & Methods: The 48 newborn Holstein calves with an average weight of 40±2 kg were used with 4 treatments and 12 replications with a factorial (2×2) in the form of a completely random design. Experimental treatments include: 1) Basic diet without supplementation, 2) Basic diet with 2 g of conjugated linoleic acid emulsified, 3) Basic diet with 500 mg of vitamin E emulsified and 4) Basic diet with 500 mg of vitamin E+2 g of conjugated linoleic acid emulsified.
Results: The supplementing the diet of calves with conjugated linoleic acid with and without vitamin E did not have a significant effect on body weight, daily weight gain, feed intake and feed conversion ratio compared to the control group. At 40 d, calves receiving conjugated linoleic acid had higher glucose concentration (P<0.05). However, the concentration of cholesterol, triglyceride, protein and albumin were not affected by the emulsifying of conjugated linoleic acid, vitamin E and their interaction effects. Supplementation of conjugated linoleic acid in the diet decreased the concentration of blood urea compared to the control group, but the addition of vitamin E had an increasing effect on blood urea (P<0.05). Total Antioxidant capacity of whole blood increased significantly by vitamin E, conjugated linoleic acid emulsion and their interaction effects (P<0.05). At 40 days, the activity of alanine aminotransferase decreased by the vitamin E (P<0.05). Glutathione peroxidase concentration was influenced by conjugated linoleic acid and vitamin E (P<0.05). Conjugated linoleic acid significantly affected the concentration of malondialdehyde and superoxide desmutase (P<0.05). The blood IL-6 concentration was affected by the factor of vitamin E and conjugated linoleic acid, so that the calves receiving the emulsion of conjugated linoleic acid and vitamin E had a lower IL-6 concentration (P<0.05). Conjugated linoleic acid supplementation significantly affected tumor necrosis factor-alpha (TNF-α). Thus, the fed calves with emulsion containing conjugated linoleic acid decreased TNF-α (P<0.05).
Conclusion: The use of conjugated linoleic acid and vitamin E in emulsified form did not improve the growth performance of calves, but it had a significant effect on the immune system and liver enzymes. |
|
| Keywords: Conjugated linoleic acid, Suckling calf, Vitamin E, Emulsion, Interleukin |
|
|
Full-Text [PDF 758 kb]
(271 Downloads)
|
Type of Study: Review |
Subject:
Special
Received: 2025/12/2 | Accepted: 2025/12/1 | Published: 2026/03/1
|
|
|
|
|
|
|
| Send email to the article author |
|
|
|
| Add your comments about this article |
|
|
|
